Shake well before use. Apply a small amount of serum into the palm of your hand and massage it into either a wet or dry coat. No rinsing is required. For external use only. Avoid contact with eyes. Irritation may occur after using any product for pets. If it persists consult your veterinarian. Keep out of the reach of children and pets. This should never substitute prescribed medication. It works best as part of a holistic approach to either dermal treatment or flea and tick control. Compatible with pharmaceutical products.